A patient of prinzmetal’s angina is staed on isosorbide mononitrate. What is the mechanism of action of nitrates in this condition?
Correct Answer: Endothelium independent coronary vasodilation
Description: Prinzmetal's angina is due to spasm of main coronary aery. Treatment is by dilatation of coronary aery. Endothelium normally generates NO, but here we are giving nitrates for generation of NO. Mechanism of action of nitrates: Preload reduction >> Afterload reduction Redistribution of coronary flow in the aerial tree action may cause orable redistribution of blood flow to ischaemic areas in angina patients.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now