Patients with hemophilia A has bleeding disorder because of-
Correct Answer: Lack of reaction accelerator during activation of factor X in coagulation cascade
Description: Haemophilia is caused by quantitative reduction of factor VIII in 90% of cases well 10% cases have normal or increased level of factor VIII with reduced activity. factor VIII activates factor X the blood coagulation pathway. But in haemophilia A due to reduced activity of factor VIII ,It can not activate factor X.Therefore , no coagulation exists and increases bleeding. Reference: textbook of Pathology ,7th edition ,author Harsha Mohan, page number 313
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now