Birbeck granules in cytoplasm is seen in ?
Correct Answer: Langerhans cell histiocytosis
Description: Ans. is 'a' i.e., Langerhans cell histiocytosis Birbeck granules are characteristic of langerhans cell histiocytosis Tumour cells in the langerhan's cell histiocvtosis are derived from dendritic cells and express : S-100 CD1a HLA-DR These cells are characterized by the presence of birbeck granules in their cytoplasm unde he electron microscope, Birbeck granules have pentalaminar, rodlike tuular appearance and sometimes a dilated terminal end (tennis-racket appearance)
Category:
Pathology
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