All of the following statements about insulin like growth factor -(IGF) are true, except(2018)
Correct Answer: Mainly secreted by the pancreas
Description: Gene for IGF is expressed in the choroid plexus and meninges,cailage, Liver and in many other tissues, indicating that they are likely synthesized in these tissues. Secretion of IGF-I is independent of growth hormone before bih but is stimulated by growth hormone after bih. Growth hormone acts on cailage to conve stem cells into cells that respond to IGF-I,Locally produced as well as circulating IGF-I then makes the cailage grow. Insulin like growth factors are also known as Somatomedin C.. Ref:-Ganong, pg num:-327
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