Mark the false statement regarding Mitochondrial DNA
Correct Answer: Dont show heteroplasmy
Description: Mitochondrial DNA 1% of cellular DNA , 16569 base pairs , 13 proteins of respiratory chain Maternal inheritance. This peculiarity exists because ova contain numerous mitochondria within their abundant cytoplasm, whereas spermatozoa contain few Shows heteroplasmy AGA and AGG are stop codon in mitochondrial DNA Complement of the zygote is derived entirely from the ovum Mothers transmit mtDNA to all their offspring, male and female Daughters but not sons transmit the DNA fuher to their progeny. Deleterious effects primarily on the organs most dependent on oxidative phosphorylation such as the central nervous system, skeletal muscle, cardiac muscle, liver, and kidneys. Diseases are rare and. EXAMPLES: Leber hereditary optic neuropathy, MELAS ; Mitochondrial Encephalopathy, Lactic acidosis and Stroke like episode. Kearne Sayre Syndrome ,is a large deletion in mitochondrial DNA MELAS, MERRF is a mutation of t RNA
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now