**Question:** Zika Virus is transmitted by

A. Aedes mosquitoes
B. Tick
C. Human-to-human contact
D. Air

**Correct Answer:** **A. Aedes mosquitoes**

**Core Concept:** Zika virus is a mosquito-borne viral infection transmitted primarily by the Aedes species of mosquitoes. Aedes mosquitoes are known to transmit other arboviral diseases like dengue, chikungunya, and yellow fever.

**Why the Correct Answer is Right:** Aedes mosquitoes are the primary vector for transmitting the Zika virus. The virus enters the mosquito body, replicates, and then is transmitted to humans during the mosquito's subsequent blood meal. The Aedes aegypti and Aedes albopictus mosquitoes are the two main species responsible for transmitting Zika virus. These mosquitoes are daytime active, unlike the night-active species like Anopheles, which transmit malaria.

**Why Each Wrong Option is Incorrect:**

**Option B (Tick):** Tick-borne diseases are caused by various pathogens, such as bacteria, viruses, and parasites. Tick-borne diseases are not associated with Zika virus transmission.

**Option C (Human-to-human contact):** Zika virus transmission can occur through human-to-human contact, but the primary mode of transmission is mosquito-borne, specifically through Aedes mosquitoes.

**Option D (Air):** Airborne transmission does not involve direct contact with an infected mosquito or vector. Airborne diseases are spread through respiratory droplets, aerosols, or contaminated surfaces, which is not the case for Zika virus transmission.

**Clinical Pearl:** Understanding the mode of transmission is crucial for public health strategies in controlling the spread of the Zika virus, as vector control measures targeting Aedes mosquitoes can help prevent Zika virus transmission. This includes the use of insect repellents, wearing protective clothing, and eliminating mosquito breeding sites in homes and communities.