Zero dose of Polio vaccine in which is give –
**Core Concept**
The zero dose of the Polio vaccine is administered to newborns to provide immediate protection against poliovirus, which is a highly infectious disease that can cause severe paralysis and death. This dose is crucial in preventing polio transmission and outbreak, especially in areas with high endemicity.
**Why the Correct Answer is Right**
The zero dose of the Polio vaccine is given at birth, typically within 6 hours of birth, to provide early protection against poliovirus. This dose is crucial in developing the infant's immune system to fight against the virus. The oral poliovirus vaccine (OPV) is the most commonly used vaccine for this purpose, which contains live, attenuated poliovirus strains. The administration of OPV at birth helps to establish a mucosal immune response, which is essential in preventing the spread of the virus.
**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the zero dose of the Polio vaccine is not administered at 6 weeks of age. The first dose of the vaccine is indeed given at 6 weeks of age, but not the zero dose.
**Option B:** This option is incorrect because the zero dose of the Polio vaccine is not administered at 14 weeks of age. The second dose of the vaccine is indeed given at 14 weeks of age, but not the zero dose.
**Option C:** This option is incorrect because the zero dose of the Polio vaccine is not administered at birth in the form of an injection. The OPV is given orally at birth.
**Clinical Pearl / High-Yield Fact**
It's essential to remember that the zero dose of the Polio vaccine is a critical component of the vaccination schedule, and its administration at birth is crucial in preventing polio transmission and outbreak.
**Correct Answer: A.**