Z-lines are anchored to the sarcolemma by:

Correct Answer: Desmin
Description: Desmin and vimentin are the proteins that anchor Z-lines to sarcolemma. a-actinin and CapZ proteins anchor the thin filaments to the Z-lines. Titin is attached to the Z-line, and it aligns the thick filament in sarcomere. Dystrophin is attached to the ends of thin filaments (toward the center of sarcomere); it extends from thin filament to sarcolemma.
Category: Physiology
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