Xeroderma pigmentosum is caused due to abnormalities in:
Correct Answer: Nucleotide excision repair
Description: Ans. B. Nucleotide excision repaira. It is transmitted as autosomal recessive and DNA repair mechanism is defective. DNA damage is produced by UV irradiation especially thymine dimers, cannot be incised. Inborn deficiency of the enzyme "nicking endonuclease" is there.b. Clinical manifestations: produces blisters on the skin.c. Dry keratosis, hyperpigmentation and atrophy of skin.d. May produce corneal ulcers.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now