Wilm’s tumor is associated with all the following except :
Correct Answer: Polycystic kidney
Description: Warn' s tamer :
Wilm's tumor, also known as nephroblastoma, is the most common malignant tumor of kidney in children. Etiology.
Most of the tumor are sporadic.
1- 2% may have family history.
Familial predisposition to wilm's tumor is inherited in an autosornal dominant manner.
Mutation of the following genes are seen in wilms tumor.
Wilms tumor gene (WT 1) on chromosome 11.
CTNNB I gene encoding the protooncogene beta - ca ten in.
p53.
Wilm's tumor is associated with three distinct syndromes.
WAGR syndrome
Beck with Wiedemnn syndrome
Denys - Drash syndrome
Wilm's tumor
Aniridia
Genital abnormalities
Mental Retardation
Enlargement of body organs
Hemihypertrophy
Renal medullary cysts
Adrenal cytomegaly : abnormal large cells in adrenal cortex
Gonadal dysgenesis (Male pseudo - hermaphrodite)
Nephropathy leading to Renal failure
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now