Pharmacology Why is a combination of Ranitidine and Sucralfate better avoided in patient with peptic ulcer disease? A Ranitidine combines with sucralfate and prevents its action B Sucralfate inhibits ranitidine absorption C Ranitidine increases the gastric pH so sucralfate is not able to act D Combination of these two drugs produces serious side effects like agranulacytosis 💡 Explanation Why is a combination of Ranitidine and Sucralfate better avoided in patient with peptic ulcer disease? ✓ Correct Answer: C. Ranitidine increases the gastric pH so sucralfate is not able to act