Okay, let's tackle this question. The user wants me to create a detailed explanation for an MCQ about whorled keratopathy. First, I need to recall what whorled keratopathy is. From what I remember, it's a corneal condition characterized by a whorled or spiral pattern of opacity. Now, the question is asking which medication causes this.

The options weren't provided, but the correct answer is missing. Let me think about common causes of corneal changes. I know that chloroquine and hydroxychloroquine are associated with retinal toxicity, but maybe they also affect the cornea. Wait, another drug that comes to mind is amiodarone. Amiodarone can cause corneal deposits, specifically a whorled pattern. Let me verify that.

Amiodarone is a class III antiarrhythmic. Its side effects include corneal microdeposits, which are typically described as whorled or fingerprint-like. This is due to the accumulation of the drug in the corneal epithelium. Other drugs like tricyclic antidepressants can cause corneal changes too, but the classic whorled pattern is more specific to amiodarone.

Now, for the incorrect options. Let's say the options include other drugs. For example, maybe chloroquine, which can cause retinal toxicity but not the same corneal pattern. Or perhaps a drug like corticosteroids, which can cause other ocular issues like glaucoma or cataracts. Another possibility is a drug like timolol, a beta-blocker, which might not be associated with this specific corneal change.

The core concept here is the recognition of drug-induced corneal changes, specifically the whorled keratopathy caused by amiodarone. The clinical pearl would be to remember that amiodarone is the key drug associated with this finding, and that it's important to monitor patients on this medication for ocular side effects.

So, the correct answer would be amiodarone. The explanation should cover the mechanism (drug accumulation in corneal cells), why other options are wrong (different side effects), and the high-yield fact about amiodarone's ocular toxicity.

**Core Concept**
Whorled keratopathy is a corneal opacity pattern caused by drug-induced lipid or pigment deposition in the corneal epithelium. It is classically associated with **amiodarone**, a class III antiarrhythmic drug, due to its high iodine content and corneal epithelium accumulation.

**Why the Correct Answer is Right**
Amiodarone contains high levels of iodine and lipophilic properties, leading to accumulation in the corneal epithelium. This results in **whorled or fingerprint-like** microdeposits, typically asymptomatic but visible on slit-lamp examination. The mechanism involves disruption of corneal epithelial cell membranes and lipid deposition, though it rarely affects vision significantly.

**Why Each Wrong Option is Incorrect**
**Option A:** *Chloroquine/hydroxychloroquine* cause retinal toxicity (e.g., maculopathy) but not whorled keratopathy.
**Option B:** *Corticosteroids* may cause glaucoma, cataracts

✓ Correct Answer: B. Amiodarone