WHO ORS composition are (mmol) –
**Core Concept:** The correct answer is referring to the composition of oral rehydration solution (ORS) used in the treatment of diarrheal diseases, particularly in the management of dehydration caused by acute gastroenteritis. ORS is a solution designed to replace fluids and electrolytes lost during diarrhea and vomiting episodes in patients.
**Why the Correct Answer is Right:** ORS contains specific concentrations of electrolytes to maintain the balance of fluids and electrolytes in the body. The correct answer represents the concentration of major electrolytes in millimoles per liter (mmol/L) in an ideal ORS solution:
1. Sodium (Na+): **Correct answer D** indicates the sodium concentration in the solution, which is crucial for maintaining osmotic balance and preventing hyponatremia.
2. Chloride (Cl-): The chloride concentration in the solution helps to maintain the overall electroneutrality by balancing the sodium and chloride ions.
3. Potassium (K+): The potassium concentration in the correct answer C is important for cellular function and to prevent hyperkalemia.
4. Calcium (Ca2+): Although calcium is not a primary component of ORS, it is included in the correct answer B to ensure adequate calcium replacement and prevent hypocalcemia.
5. Magnesium (MgΒ²βΊ): The magnesium concentration in the correct answer A is essential for cellular function and neuromuscular function and to prevent hypomagnesemia.
6. Glucose: The glucose concentration in the correct answer A helps to maintain blood glucose levels and provides energy for the cells.
7. Glucose: The glucose concentration in the correct answer A helps to maintain blood glucose levels and provides energy for the cells.
8. Sugar-electrolyte ORS (SES): The sugar-electrolyte ORS (SES) is an alternative term for the balanced ORS solution mentioned above.
**Why Each Wrong Answer is Incorrect:**
1. Option A (120 mmol/L): This option has an extremely high glucose concentration, which may lead to osmotic diarrhea, worsening dehydration, and causing the patient to become hyperglycemic.
2. Option B (100 mmol/L): This option has a lower glucose concentration, but still higher than the correct answer A. This could lead to inadequate energy supply for cells and potential hypoglycemia.
3. Option C: This option has a lower glucose concentration, closer to the correct answer C, but still deviates from the ideal glucose concentration required to maintain blood glucose levels and provide energy for cells.
4. Option D: This option has a lower glucose concentration, closely matching the correct answer C, but still deviates from the ideal glucose concentration required for energy supply to cells.
**Clinical Pearl:** In severe cases of dehydration due to diarrhea, rehydration therapy should be initiated using balanced ORS (option D) or sugar-electrolyte ORS (SES), which closely matches the correct answer C, to maintain blood glucose levels and provide energy to cells. The glucose concentration should ideally be around 110-120