Which toll like receptors are involved in action of bacterial endotoxins –
Correct Answer: II
Description: Ans. is 'b' i.e., II o Ten different mammalian Toll like receptors (TRRs) have been identified --> TLR 1 to 10. o TLRs are involved in responses to widely divergent types of molecules that are commonly expressed by microbial but not mammalian cells. TLR Microbial ligand molecules Peptidoglycan of Gram (+)ve bacteria zymosan of fungi GPI anchor of Trypanosomes Lipoarabinomannan of mycobacteria LPS (endotoxin) of Leptospira Lipoproteins of bacteria Double - stranded DNA of viruses LPS (endotoxin) of all other gram (-)ve bacteria HSF 00 of chlamydia Flagellin of bacteria CpG DNA of bacteria and protozoa Note ? o Bacterial endotoxin of all gram (-)ve organisms, bind to TLR-4, except Leptospira. o Endotoxin of leptospira binds to TLR-2.
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now