Pathology Which test is most specific for the detection of syphilis? A Rapid plasmin reagin (RPR) B Fluorescent treponemal antibody-absorption (FTA-ABS) C Venereal Disease Research Laboratory (VDRL) D Ziehl-Neelsen stain 💡 Explanation Which test is most specific for the detection of syphilis? ✓ Correct Answer: B. Fluorescent treponemal antibody-absorption (FTA-ABS)