Which receptors are blocked in Myasthenia Gravis.
Correct Answer: Ach receptors
Description: Ref. Guyton. 13th edition. Page. 96
Myasthenia gravis is an autoimmune disease characterized by autoantibodies against the acetylcholine (ACh) receptor of the neuromuscular junction, result- ing in muscular weakness predominantly affecting the facial muscles. Females are affected more frequently than males.
Extra ocular muscle weakness may lead to ptosis and diplopia; the weakness worsens with repeated contractions.
Respiratory muscle involvement may lead to death.
There is an association with thymic hyperplasia and thymomas.
Treatment is anticholinesterase agents, steroids, and thymectomy.
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