## **Core Concept**
The question tests knowledge of a specific biochemical phenomenon related to protein precipitation and solubility. The correct answer involves understanding the properties of certain proteins or substances that exhibit unique behavior at specific temperatures.
## **Why the Correct Answer is Right**
The correct answer, Bence Jones proteins, are abnormal proteins (light chains) found in the urine of patients with multiple myeloma. A characteristic feature of Bence Jones proteins is that they precipitate at temperatures between 50°C to 60°C but redissolve at higher temperatures. This property is utilized in their detection.
## **Why Each Wrong Option is Incorrect**
- **Option A:** This option is incorrect because it does not correspond with known substances that exhibit the described thermal precipitation behavior.
- **Option C:** This option is incorrect as it does not relate to substances known for precipitating within the specified temperature range and redissolving upon further heating.
- **Option D:** This option is incorrect because it does not accurately represent substances with the unique thermal solubility properties described.
## **Clinical Pearl / High-Yield Fact**
Bence Jones proteins are an important diagnostic marker for multiple myeloma, a type of plasma cell dyscrasia. Their detection, particularly through the characteristic thermal precipitation test, is a classic laboratory technique. Remembering that these proteins precipitate at 50°C-60°C but dissolve at higher temperatures can aid in quick identification during exams.
## **Correct Answer:** B. Bence Jones proteins
Free Medical MCQs · NEET PG · USMLE · AIIMS
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