Which one of the following statements is best suited for isolated polymyalgia rheumatica?
Correct Answer: Response to oral coicosteroids typically occurs within seven days
Description: Patients with isolated polymyalgia rheumatica respond promptly to prednisone, which can be staed at a lower dose of 10-20 mg/dl . Similar to giant cell aeritis, the ESR can serve as a useful indicator in monitoring and prednisone reduction. Recurrent polymyalgia symptoms develop in the majority of patients during prednisone tapering. One study of weekly methotrexate found that the use of this drug reduced the prednisone dose on average by only 1 mg and did not decrease prednisone-related side effects. A randomized trial in polymyalgia rheumatica did not find infliximab to lessen relapseor glucocoicoid requirements. Ref - Harrisons 20e p2585
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