Pathology Which one of the following statements about Hemoglobin S (HbS) is not true – A Hemoglobin HbS differs from hemoglobin HbA by the substitution of Val for Glu in position 6 of the beta chain B One altered peptide of HbS migrates faster towards the cathode (-) than the corresponding peptide of HbA C Binding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the red blood cells D Lowering the concentration of deoxygenated HbS can prevent sickling 💡 Explanation Which one of the following statements about Hemoglobin S (HbS) is not true - ✓ Correct Answer: C. Binding of HbS to the deoxygenated HbA can extend the polymer and cause sickling of the red blood cells