Pharmacology Which one of the following statement about imipenem is most accurate ? A The drug has a narrow spectrum of anti-bacterial action B It is used in fixed combination with sulbactam C Imipenem is highly susceptible to beta lactamase produced by enterobacteriaciae D In renal dysfunction, dosage reduction are necessary to avoid seizures 💡 Explanation Which one of the following statement about imipenem is most accurate ? ✓ Correct Answer: D. In renal dysfunction, dosage reduction are necessary to avoid seizures