Injection Sclerotherapy in Varicose veins Sodium tetradecyl sulphate is most commonly used Destroys lipid membranes of endothelial cells causing them to shed, leading to thrombosis, fibrosis and sclerosis Sclerosing agents These are irritants causing inflammation, coagulation and ultimately fibrosis, when injected into hemorrhoids or varicose veins Used only for local injection Sclerosing agents are Phenol(5%) in almond oil or peanut oil Ethanolamine oleate (5%) in 25% glycerin and 2% benzyl alcohol Polidocanol(3%) Sodium tetradecyl sulphate (3%) with benzyl alcohol (2%) Hypeonic saline Ref : Sabiston 20th edition Pgno :1835