**Question:** Which one of the following is not true regarding Centchroman?

A. Centchroman is a progestin-only contraceptive medication
B. Centchroman is used for post-coital contraception
C. Centchroman has estrogen-like effects on the body
D. Centchroman is effective in preventing pregnancy in women with coagulation disorders

**Correct Answer: C. Centchroman has estrogen-like effects on the body:**

Centchroman is a progestin-only contraceptive medication, which belongs to the class of progestogens. Progestogens are synthetic hormones that mimic the actions of progesterone, a natural hormone produced in the body. Unlike estrogens, which are responsible for the female sex characteristics and menstrual cycle regulation, progestogens primarily regulate the endometrial lining and prevent implantation.

Centchroman is primarily used in combination with another medication called ethinylestradiol (a synthetic estrogen) to form the oral contraceptive pill, called Chlormadinone acetate. In this combination, the estrogen component provides additional contraceptive benefit by suppressing the menstrual cycle.

Centchroman does not possess estrogen-like effects on the body, as it is a progestogen and not an estrogen. Estrogen is responsible for the estrogenic actions, such as stimulating breast development, fat distribution, and maintaining bone density. Estrogen's role in menstrual cycle regulation is distinct from that of progestogens like Centchroman.

**Why the Correct Answer is A and B are True:**

A. Centchroman is an effective contraceptive medication that prevents pregnancy when taken regularly as prescribed.
B. Centchroman can be used for post-coital contraception, meaning it can be taken up to 5 days after unprotected intercourse to reduce the risk of pregnancy.

**Why option D is False:**

Centchroman is not effective in women with coagulation disorders. This is due to its progestogenic action, which can interfere with the clotting process and increase the risk of bleeding and thrombosis in women with coagulation disorders. In contrast, estrogen-based medications are often used in women with coagulation disorders as they can improve the clotting process.

**Why option C is False:**

Centchroman does not have estrogen-like effects, as mentioned earlier. It is a progestogen, which has distinct pharmacological actions compared to estrogens. The estrogen component is responsible for estrogenic effects, while the progestogen component is responsible for actions like preventing implantation, maintaining the endometrial lining, and suppressing ovulation.