## **Core Concept**
The question tests knowledge of medications that can cause ocular toxicity, which refers to harmful effects on the eye. Oculotoxic drugs can cause a range of adverse effects, from mild irritation to severe vision loss. This question requires the test-taker to identify a specific drug known for its oculotoxic properties.
## **Why the Correct Answer is Right**
Chloroquine is well-documented to have oculotoxic effects, particularly with long-term use. It can cause **retinopathy**, leading to visual disturbances and potentially irreversible vision loss. The mechanism involves the accumulation of chloroquine in the retinal pigment epithelium, causing toxicity to the photoreceptors. This effect is dose-dependent and more common with prolonged use or at higher doses.
## **Why Each Wrong Option is Incorrect**
- **Option A:** While certain anesthetics can have ocular effects, they are not typically classified as oculotoxic in the same direct manner as chloroquine.
- **Option B:** This option does not provide a clear drug name, making it impossible to assess its oculotoxic potential.
- **Option D:** Without a specific drug name, it's not possible to evaluate its potential for oculotoxicity.
## **Clinical Pearl / High-Yield Fact**
A key point to remember is that patients on long-term chloroquine therapy should have regular ophthalmologic examinations to monitor for early signs of retinopathy. Early detection can prevent further toxicity by adjusting the dose or switching to a different medication.
## **Correct Answer:** C. Chloroquine.
Free Medical MCQs Β· NEET PG Β· USMLE Β· AIIMS
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