Which one of the following blood fractions is stored at – 40degC?-
**Core Concept**
Blood fractions are categorized based on their storage requirements, which primarily depend on their sensitivity to temperature and the risk of degradation. The storage temperature for each fraction is crucial to maintain their viability and effectiveness.
**Why the Correct Answer is Right**
The correct answer is **B. Cryoprecipitate**. Cryoprecipitate is a blood fraction that is rich in fibrinogen, factor VIII, and von Willebrand factor. It is stored at -40°C to preserve these labile clotting factors. The low temperature prevents the degradation of these proteins, ensuring their potency and effectiveness when used in clinical settings.
**Why Each Wrong Option is Incorrect**
**Option A:** Plasma is typically stored at -20°C, not -40°C. It contains a wide range of clotting factors, but not in the same concentration as cryoprecipitate.
**Option C:** Platelet concentrates are usually stored at room temperature (20-24°C) or at 22°C with agitation. They require specific conditions to maintain their viability and function.
**Clinical Pearl / High-Yield Fact**
Cryoprecipitate is used to treat patients with fibrinogen deficiency, such as those with fibrinogenemia or after massive transfusions. It is also used to enhance clotting in patients with severe bleeding.
**Correct Answer:** B. Cryoprecipitate