Gynaecology & Obstetrics Which one of the following biochemical parameters is the most sensitive to detect open spina A Maternal serum alpha fetoprotein B Amniotic fluid alpha fetoprotein C Amniotic fluid acetyl cholinesterase D Amniotic fluid glucohexaminase 💡 Explanation Which one of the following biochemical parameters is the most sensitive to detect open spina ✓ Correct Answer: C. Amniotic fluid acetyl cholinesterase