Pharmacology Which of the following statements is NOT TRUE about NSAIDs? A Acetyl salicylic acid is an irreversible inhibitor of COX enzyme. B Acetyl salicylic acid reduces in vivo synthesis of prostaglandins. C Its clearance is independent of plasma concentration. D Antiplatelet effect of low dose aspirin is related to pre-systemic COX inhibition. 💡 Explanation Which of the following statements is NOT TRUE about NSAIDs? ✓ Correct Answer: C. Its clearance is independent of plasma concentration.