**Core Concept**
The question tests the understanding of viral genetics, specifically the types of RNA found in different viruses. **Negative-sense RNA** refers to a type of single-stranded RNA that requires transcription to a complementary positive-sense RNA before it can be translated into proteins.

**Why the Correct Answer is Right**
The correct answer is related to the **Influenza virus**, which indeed has a **negative-sense single-stranded RNA** genome. This type of RNA is characteristic of certain viral families, including Orthomyxoviridae, which includes the Influenza virus. The **RNA-dependent RNA polymerase** is crucial for the replication of these viruses.

**Why Each Wrong Option is Incorrect**
**Option A:** This option is incorrect because the specific virus mentioned here does not have negative-sense RNA.
**Option B:** Similarly, this option is incorrect as it does not pertain to a virus known for having negative-sense RNA.
**Option D:** This option is also incorrect as the virus it refers to does not have the characteristics of negative-sense RNA viruses.

**Clinical Pearl / High-Yield Fact**
It's crucial to remember that viruses with **negative-sense RNA** require a specific mechanism for replication, involving the **RNA-dependent RNA polymerase**, which is a key target for antiviral drugs.

**Correct Answer:** D. Influenza virus.