Which of the following vasculitis is not seen in adults?
## Core Concept
Kawasaki disease is a type of vasculitis that primarily affects children. It is characterized by inflammation in the walls of medium-sized arteries throughout the body. The condition is known for its acute onset and is often associated with coronary artery involvement.
## Why the Correct Answer is Right
Kawasaki disease is predominantly a pediatric condition, with the majority of cases occurring in children under the age of 5. The disease involves the inflammation of blood vessels, which can lead to serious complications, such as coronary artery aneurysms. Due to its primary occurrence in children, it stands out as not typically seen in adults.
## Why Each Wrong Option is Incorrect
* **Option A:** Giant cell arteritis is a form of vasculitis that is indeed seen in adults, particularly those over the age of 50. It primarily affects the large and medium-sized arteries, with a notable predilection for the temporal arteries.
* **Option B:** Takayasu arteritis is another form of vasculitis that affects large vessels, primarily the aorta and its major branches. It typically presents in young adults, making it a condition seen in adults.
* **Option D:** Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis that affects medium-sized muscular arteries. PAN can occur at any age but is more commonly seen in adults.
## Clinical Pearl / High-Yield Fact
A key clinical pearl is that Kawasaki disease is the leading cause of acquired heart disease in children in developed countries. Early diagnosis and treatment are crucial to prevent cardiac complications. A helpful mnemonic to remember some of the key diagnostic criteria for Kawasaki disease is "CRASH and BURN": Conjunctivitis, Rash, Adenopathy, Sterile pyuria, and BURNing fever, along with changes in the extremities.
## Correct Answer: C. Kawasaki disease.