**Core Concept**
Vaccination at birth is a crucial step in preventing infectious diseases and ensuring the health of newborns. Hepatitis B vaccination is recommended for all newborns within the first 24 hours of life, as it protects against hepatitis B virus (HBV) infection, which can cause liver disease, liver cancer, and liver failure.

**Why the Correct Answer is Right**
The hepatitis B vaccine is given at birth because it provides immediate protection against HBV infection. This is particularly important for newborns, as they are at high risk of acquiring HBV infection from their infected mothers during delivery. The hepatitis B vaccine works by stimulating the production of antibodies against the HBV surface antigen (HBsAg). These antibodies help to neutralize the virus and prevent infection. The vaccine is administered intramuscularly, typically in the thigh or arm, and is usually given in combination with other vaccines, such as the hepatitis A vaccine.

**Why Each Wrong Option is Incorrect**
* **Option A:** There is no vaccine that is universally given at birth, except for the hepatitis B vaccine.
* **Option B:** The rotavirus vaccine is usually given to infants in a series of doses starting at 2 months of age, not at birth.
* **Option C:** The Hib (Haemophilus influenzae type b) vaccine is given to infants in a series of doses starting at 2 months of age, not at birth.
* **Option D:** The pneumococcal conjugate vaccine is given to infants in a series of doses starting at 2 months of age, not at birth.

**Clinical Pearl / High-Yield Fact**
The hepatitis B vaccine is a critical component of newborn immunization, and it is essential to ensure that all newborns receive this vaccine within the first 24 hours of life to prevent HBV infection.

**Correct Answer:** C.