**Core Concept:** Hoffmann elimination is a chemical reaction in organic chemistry, often used to study the structure of amino acids, particularly those containing an imino or amino group. It is a type of elimination reaction involving the loss of water (H2O) and ammonia (NH3) to form an amine group.

**Why the Correct Answer is Right:** Alkaline hydrolysis of an amino acid containing an imino group, such as L-glutamine, is the key to Hoffmann elimination. When the reaction is carried out in the presence of a strong base like sodium hydride (NaH) or sodium methoxide (MeONa), the amino acid undergoes deprotonation at the imino nitrogen (N-δ) and carbonyl oxygen, followed by elimination of water and ammonia to form an amine group. This process is also known as "N-alkylation of amino acids."

**Why Each Wrong Option is Incorrect:**

A. This option is incorrect because it refers to the incorrect amino acid, which does not undergo Hoffmann elimination.
B. This option is incorrect because the amino acid does not contain an imino group, which is necessary for Hoffmann elimination.
C. This option is incorrect because the amino acid does not contain an imino group, making it incapable of undergoing Hoffmann elimination.
D. This option is incorrect because the amino acid does not contain an imino group, preventing it from undergoing Hoffmann elimination.

**Clinical Pearl:** Hoffmann elimination plays a significant role in understanding the structure of amino acids, particularly those containing imino groups. This process helps determine the stereochemistry of amino acids and their interactions with other molecules, providing valuable insights for pharmacology, biochemistry, and molecular biology research.