Skin Which of the following tests would be MOST useful for confirmation of Pemphigus vulgaris? A Bacterial culture B Complete blood count C Fungal culture D Tissue biopsy with direct immunofluorescence 💡 Explanation Which of the following tests would be MOST useful for confirmation of Pemphigus vulgaris? ✓ Correct Answer: D. Tissue biopsy with direct immunofluorescence