Which of the following suppress the activity of osteoblasts?
Correct Answer: Coicosterone
Description: Steroid causes inhibition of osteoblast function and potential increase in osteoblast apoptosis, resulting in impaired synthesis of new boneStimulation of bone resorption, probably as a secondary effectImpairment of the absorption of calcium across the intestine, probably by a vitamin D-independent effectIncrease of urinary calcium loss and induction of some degree of secondary hyperparathyroidismReduction of adrenal androgens and suppression of ovarian and testicular secretion of estrogens and androgensPotential induction of glucocoicoid myopathy, which may exacerbate effects on skeletal and calcium homeostasis, as well as increase the risk of falls.
Category:
Pathology
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