**Core Concept**
Steroids administered by inhalation are used to manage respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). These inhaled steroids act locally in the lungs, reducing inflammation and preventing bronchospasm.

**Why the Correct Answer is Right**
Inhaled steroids, such as fluticasone, bind to glucocorticoid receptors in the lungs, leading to anti-inflammatory effects. They decrease the expression of inflammatory genes, reduce the production of pro-inflammatory cytokines, and inhibit the infiltration of inflammatory cells into the airways. This results in improved lung function and reduced symptoms in patients with respiratory diseases.

**Why Each Wrong Option is Incorrect**
**Option A:** Corticosteroids like prednisolone are systemically active and cannot be administered by inhalation due to their rapid absorption and distribution throughout the body.
**Option B:** Betamethasone is a potent corticosteroid, but it is not commonly administered by inhalation. Its use is more often associated with intravenous or intramuscular injections.
**Option C:** Triamcinolone is a corticosteroid with some degree of local activity, but it is not typically administered by inhalation. Its use is more often associated with topical or parenteral formulations.

**Clinical Pearl / High-Yield Fact**
Inhaled steroids are preferred over systemic corticosteroids for long-term management of asthma and COPD due to their localized effects, reduced risk of systemic side effects, and improved patient compliance.

**Correct Answer:** C. Fluticasone.