Which of the following statements is true regarding enzyme inhibition?

A. Sulfonamides inhibit folate reductase irreversibily

B. Ethanol inhibits aldehyde dehydrogenase when used in methanol poisoning

C. Acetylcholinesterase inhibition by malathion can be reversed by increasing the levels of Acetylcholine

D. Fluoroacetate competitively inhibits Aconitase

Correct Answer: Fluoroacetate competitively inhibits Aconitase

Description: Sodium flouroacetate compete with acetic acid and form flouroacetic acid .This inhibit TCAcycle by poisoning aconitase enzyme activity. Ref: Perspective in mycological research by Perspective in mycological research, The encyclopedia of nutrition and good health By Robe A. Ronzio page 436; Medical toxicology By Richard C. Da page 65.

Category: Biochemistry

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