Which of the following statements is false regarding bedaquiline?
Correct Answer: Inhibits mycobacterial cell wall synthesis
Description: Bedaquiline is a new tubercular drug which inhibits mycobacterial ATP synthase . Resistance occurs by mutation to ATP synthase and efflux pimp. Terminal half life is high about 160 days. Adverse effects are QR prolongation and hepatotoxicity. It is indicated for MDR TB and XDR TB. Other drugs are Delaminid and Pretomanid. So first option is better one.
Category:
Pharmacology
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