Pharmacology Which of the following statements about the fluoroquinolones is FALSE? A Gonococcal resistance to fluoroquinolones may involve changes in DNA gyrase B Modification of fluoroquinolones dosage is required in patients if creatinine clearance is less than 50 mL/min C A fluoroquinolone is the drug of choice for treatment of an uncomplicated urinary tract infection in a 7 year-old girl D Fluoroquinolones inhibit relaxation of positively supercoiled DNA 💡 Explanation Which of the following statements about the fluoroquinolones is FALSE? ✓ Correct Answer: C. A fluoroquinolone is the drug of choice for treatment of an uncomplicated urinary tract infection in a 7 year-old girl