Which of the following statements about Diabetes Insipidus is true

Which of the following statements about Diabetes Insipidus is true –

A. Urine osmolality should be > 300 mosm/L

B. Plasma osmolality should be < 280 mmol/L

C. Water deprivation test is required

D. Plasma osmolality should be > 300 mosm/L prior to H2O Deprivation test

Correct Answer: Water deprivation test is required

Description: In diabetes insipidus, urine is not maximally concentrated (osmolality below 600 mOsm/kg) in the presence of increased plasma osmolality (greater than 300 mOsm/kg). The diagnosis can be confirmed or refuted by random simultaeous samples of blood and urine, but more often a dynamic test like water deprivation test is required. Reference : page 794 Davidson's Principles and practice of Medicine 22nd edition

Category: Medicine

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