Which of the following statements about baricitinib is FALSE?
Correct Answer: Approved for use in moderate to severe Crohn's disease
Description: Baricitinib andtofacitinib are oral JANUS kinase inhibitors (JAK). These drugs are used in rheumatoid ahritis.Tofacitinib is also used in ulcerative colitis. Major side-effects of these drugs are:* Increased risk of infection: TB , Herpes zoster.* Increased risk of malignancy like Lymphoma.* Hyperiglyceridemia.They require dose reduction in kidney and liver failure. So, they are avoided in lymphopenia and anemia.So, the answer is 'B' because it is not used in Crohn's disease.
Category:
Pharmacology
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