Which of the following statements about amoebicides is LEAST accurate?
Correct Answer: Paromomycin is effective in extraintestinal amoebiasis
Description: Paromomycin and diloxanide furoate are luminal ameobicides. Paromomycin is an efficacious luminal amoebicide, achieving similar or even better clearing of cysts from stools compared to diloxanidc furoate in asymptomatic cyst passers. It is an aminoglycoside antibiotic which closely resembles neomycin. Metronidazole is the main drug in intestinal ameobiasis. Emetine is a potent and directly acting amoebicide - kills trophozoites but has no effect on cysts. It is a local irrirant and has high systemic toxicity, viz, nausea, vomiting (due to CTZ stimulation and gastric irritation), abdominal cramps, diarrhoea, weakness, stiffness of muscles, myositis, hypotension, ECG changes and myocarditis. Hence it is contraindicated in pregnancy and in patients with cardiac disease.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now