Pharmacology Which of the following statements about a drug having high plasma protein binding is true? A Volume of distribution of the drug is very high B This drug will be filtered quickly by glomerulus C This drug is likely to have minimum chances of drug interactions D High plasma protein binding decreases the volume of distribution 💡 Explanation Which of the following statements about a drug having high plasma protein binding is true? ✓ Correct Answer: D. High plasma protein binding decreases the volume of distribution