Which of the following shows functional assessment of B1 deficiency:
Correct Answer: RBC Transketolase
Description: Ans. (a) RBC TransketolaseRef: Harpers Biochemistry 30th Ed; Page No- 556*Biochemical assessment of Thiamin nutritional status done by erythrocyte transketolase activation.* The activation of apo-transketolase (the enzyme protein) in erythrocyte lysate by thiamin diphosphate added in vitro has become the accepted index of thiamin nutritional status.Functional Assessment of Vitamin B complexVitamin B complexBiochemical assessmentThiamine (B1)Erythrocyte transketolase activity is reduced.Riboflavin (B2)Measurement of activation of Erythrocyte Glutathione Reductase by FAD added in vitro.Pyridoxine (B6)* Erythrocyte Transaminase activity* Tryptophan load test-measurement of Xanthurenic acid following Tryptophan load.Folic Acid (B9)* Serum folate* Serum Homocysteine* Histidine Load test or FIGLU excretion test* Peripheral Blood smear (Macrocytes , tear drop cells, hypersegmented neutrophils, anisopoikilocytosis)* Red cell folate* AICAR (Amino Imidazole Carboxamide Ribose 45 phosphate) Excretion TestCobalamin (B12)* Serum Homocysteine* Serum Cobalamin* Schilling Test using radioactive labelled coablt-60* Serum Methyl Malonate* Urine Homocysteine and MMA* Bone marrow and Peripheral blood smear
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now