Medical MCQ-Which of the following sequence is directed in a retrograde manner to EPR in COP-1 vesicles?

Which of the following sequence is directed in a retrograde manner to EPR in COP-1 vesicles?

KDEL

KDAL

DALK

KDUL

Question Category:

Biochemistry

Correct Answer:

KDEL

Description:

KDEL sequence ( lysine - aspaate - glutamate - leucine ) at carboxy terminal first travel to GA in COP-2 vesicles, interact with their specific receptor protein. then they return in a COP-1 vesicle to EPR, get dissociate from their receptor & are retrieved. Reference: Harper; 30th edition

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