**Core Concept**
Selective serotonin reuptake inhibitors (SSRIs) are a class of medications that increase serotonin levels in the brain by blocking its reuptake. However, some SSRIs can cause hepatotoxicity, a condition characterized by liver damage and inflammation.

**Why the Correct Answer is Right**
Hepatotoxicity is a rare but serious side effect of some SSRIs. One of the mechanisms underlying this effect is the inhibition of certain liver enzymes, such as cytochrome P450 3A4 (CYP3A4). This enzyme is responsible for metabolizing many drugs, including some SSRIs. When SSRIs inhibit CYP3A4, they can lead to increased levels of the medication in the body, which can cause liver damage. Additionally, some SSRIs may directly cause liver inflammation and damage through other mechanisms, such as oxidative stress and mitochondrial dysfunction.

**Why Each Wrong Option is Incorrect**
* **Option A:** This option is not a valid SARI (serotonin antagonist and reuptake inhibitor). SARIs are a distinct class of medications that have a different mechanism of action than SSRIs.
* **Option B:** This option is not known to cause hepatotoxicity. While some SSRIs can cause liver damage, this option is not a known risk.
* **Option C:** This option is not a valid SARI. SARIs are a distinct class of medications that have a different mechanism of action than SSRIs.

**Clinical Pearl / High-Yield Fact**
When prescribing SSRIs, it is essential to monitor liver function tests (LFTs) regularly, especially in patients with pre-existing liver disease. This can help identify hepatotoxicity early, allowing for prompt treatment and minimizing liver damage.

**Correct Answer: C.**