Which of the following renal tumours is associated with tuberous sclerosis?
Correct Answer: Angiomyolipoma
Description: Angiomyolipoma of kidney: Benign tumour consists of vessels, smooth muscle, and fat originating from perivascular epithelioid cells. Present in 25% to 50% of patients with tuberous sclerosis, a disease caused by loss-of-function mutations in the TSC1 or TSC2 tumor suppressor genes. Tuberous sclerosis is characterized by: lesions of the cerebral coex that produce epilepsy and intellectual disability, a variety of skin abnormalities (sebaceous adenomas, etc.), unusual benign tumors at other sites, such as the hea
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Pathology
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