Pharmacology Which of the following provides the best explanation for neostigmine being preferred over physostigmine for treating myasthenia gravis? A It is better absorbed orally B It has longer duration of action C It has additional direct agonistic action on nicotinic receptors at the muscle end plate D It penetrates blood brain barrier 💡 Explanation Which of the following provides the best explanation for neostigmine being preferred over physostigmine for treating myasthenia gravis? ✓ Correct Answer: C. It has additional direct agonistic action on nicotinic receptors at the muscle end plate