Which of the following pathway is seen in basal cell carcinoma
Correct Answer: Sonic Hedgehog
Description: Answer- B. Sonic HedgehogBasal cell carcinomaLocally aggressive tumorAssociated with mutations which activate Hedgehog pathway signalling.Gorlin syndrome is associated with gene PTCH, a tumor suppressor genePTCh is receptor for Sonic hedgehog, which determines polarity during embryonic development.Basal cell carcinoma presents as pearly papules.
Category:
Pathology
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