Which of the following mutation is seen in Cowden syndrome?
Correct Answer: PTEN mutation
Description: Mutation in PTEN gene: Breast tumors Endometrial tumors Skin appendage tumors Thyroid tumors Cowden syndrome: Dysplastic gangliogliocytoma of the cerebellum (Lhermitte Duclos disease), caused by mutations in PTEN resulting in PI3K/AKT signaling pathway PTEN
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Pathology
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