Which of the following is wrong about Afrezza?
## Core Concept
Afrezza is a type of insulin medication used to manage blood sugar levels in adults with type 1 and type 2 diabetes. It is an inhalation powder form of insulin, providing a rapid-acting insulin option. Understanding its characteristics is crucial for diabetes management.
## Why the Correct Answer is Right
Afrezza works by mimicking the body's natural insulin response to meals, helping to lower blood glucose levels. It is a rapid-acting insulin that starts working within 12-15 minutes after inhalation, peaks in about 30-45 minutes, and continues to work for 2-3 hours. This profile makes it suitable for use at mealtimes to manage postprandial glucose spikes.
## Why Each Wrong Option is Incorrect
- **Option A:** If this option incorrectly states that Afrezza is a long-acting insulin, it would be wrong because Afrezza is specifically designed as a rapid-acting insulin.
- **Option B:** If this option suggests Afrezza is administered via injection, it would be incorrect because Afrezza is unique in that it is administered via inhalation.
- **Option C:** If this option inaccurately describes Afrezza's onset or duration of action, it would be wrong based on the established pharmacokinetic profile of Afrezza.
- **Option D:** Since we do not have the specific details of the options provided, we focus on the nature of Afrezza being rapid-acting and inhaled.
## Clinical Pearl / High-Yield Fact
A key point to remember about Afrezza is that it requires patients to have a forced expiratory volume in one second (FEV1) of β₯ 1.5 L, indicating that lung function must be relatively preserved to ensure safe and effective use of the medication. This highlights the importance of pulmonary function tests before initiating Afrezza.
## Correct Answer: D.