Which of the following is typical of apoptosis?
Correct Answer: Activation of endogenous endonucleases
Description: Apoptosis is characterized by the activation of endonucleases, which leads to DNA fragmentation. The chromatin of apoptotic nuclei appears clumped as inpyknosism, but karyolysis does not occur. Nuclei may become fragmented, but this fragmentation is distinct from the mitotic division. Apoptosis does not induce an influx of inflammatory cells, and the dead cell fragments are taken up by adjacent cells in the tissue itself. Similar to other forms of cell death, apoptosis is associated with an influx of calcium into the cytosol.
Category:
Pathology
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