Which of the following is true regrading hCG: September 2010
Wait, the question is from September 2010, so maybe it's an older exam. Common hCG facts include its role in pregnancy tests because it's detectable in urine. Also, hCG has a structure similar to LH, which might explain some of its effects. The beta subunit is unique and used in pregnancy tests.
If the correct answer is about maintaining the corpus luteum, then that's a key point. Other possible options might be about its role in lactation, which is prolactin's job, or maybe about stimulating ovulation, which is FSH/LH. Another common misconception is that hCG stimulates the testes, but that's not its primary role.
The user's correct answer is the one about corpus luteum maintenance. So the explanation should highlight that hCG prevents regression of the corpus luteum, ensuring progesterone production until the placenta takes over. For the wrong options, like if one says it's produced by the ovary, that's incorrect because it's the placenta. Another wrong option might claim it's involved in milk production, which is prolactin. Also, if an option states it's a glycoprotein, that's actually true, but maybe not the main point here. Wait, hCG is a glycoprotein hormone, yes. But if the question is about its function, then the main point is corpus luteum maintenance.
Clinical pearl: hCG is detected in pregnancy tests because of its unique beta subunit. Also, it's used in fertility treatments to trigger ovulation, mimicking LH surge. But the primary function in pregnancy is corpus luteum support.
Need to make sure the explanation is concise and covers the core concept, correct answer explanation, why others are wrong, and a high-yield fact. Let me structure it as per the user's instructions.
**Core Concept:** Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by the placenta during pregnancy. Its primary role is to sustain the corpus luteum during early gestation, ensuring continued progesterone production to support the endometrium.
**Why the Correct Answer is Right:**
hCG prevents regression of the corpus luteum by mimicking luteinizing hormone (LH), thereby maintaining progesterone secretion. This is critical until placental steroidogenesis becomes sufficient (around 8–10 weeks of gestation). The hormone’s beta subunit is unique and targets the LH receptor, distinguishing it from other glycoprotein hormones like LH or FSH.
**Why Each Wrong Option is Incorrect:**
**Option A:** If claiming hCG is produced by the ovary, it’s incorrect because hCG is synthesized by syncytiotrophoblast cells of the placenta.
**Option B:** If suggesting hCG stimulates milk production, this